The San Francisco 49ers lost 20-17 to the Seattle Seahawks in the final minutes of the divisional matchup Sunday.

The San Francisco 49ers have officially ruled out tight end George Kittle for Sunday’s game against the Seattle Seahawks.

Just last weekend Christian McCaffrey made his triumphant return to the San Francisco 49ers as they took down the Tampa Bay ...

Kyle Shanahan and the San Francisco 49ers got a very important injury update before the game against the Seahawks.

On Friday, San Francisco 49ers head coach Kyle Shanahan addressed the media for the final time before the team’s Week 11 game ...

San Francisco 49ers cornerback Deommodore Lenoir is a rising star. And this week, the 49ers treated him as such, rewarding ...

San Francisco 49ers QB Brock Purdy sprinted to the end zone for a touchdown in the team's Week 11 matchup against the ...

San Francisco 49ers tight end George Kittle missed the game against the Seattle Seahawks with a hamstring injury ...

San Francisco 49ers DL Yetur Gross-Matos tracked down Seahawks quarterback Geno Smith for his first sack as a member of the ...

If the 49ers (5-5) fail to win a third straight division title, it will be their collapses to divisional foes that ruin them.

Niners star tight end George Kittle is unlikely to play Sunday against the Seahawks because of a hamstring injury, sources ...